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10.1016/j.cell.2013.12.010 30

Dehydration is one of the most common causes of headaches, constipation, and fatigue during GLP 1 therapy

Newer medications like retatrutide and mazdutide are in development or early commercialization, each with their own pharmacokinetic profiles and dosing schedules

However, these studies were not specifically designed to assess bone health as a primary outcome

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The table below summarizes the emerging candidates