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We have a full summary of all the major pre-clinical studies and trials below, but as Reta is in Phase III, it's clear that: It showed significant benefit and low safety risk during pre-clinical trials to justify clinical trials

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Combinative treatment of -elemene and cetuximab is sensitive to KRAS mutant colorectal cancer cells by inducing ferroptosis and inhibiting epithelial-mesenchymal transformation

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G.KanayaA.StrotmeyerE.KosterA.et al (2011)

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