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Interestingly, the smaller progenitor zone in sygl-1 mutants corresponds to the region where LST-1 is expressed, suggesting that SYGL-1 expression sets up the GSC pool size, and in its absence LST-1 determines the pool size (Shin et al., 2017)

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4 Disruption of the glutamine-glutamate cycle can lead to bipolar disorder, anxiety, depression, and addiction

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