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In the few individuals who did have preexisting cross-reactive antibodies, these often targeted the S2 region of spike that is more conserved across coronaviruses but that predominantly induces nonneutralizing antibodies [72, 73]

Si se prefiere esta ltima, puede ser aplicada en forma directa o diluida en soluciones intravenosas

Cancer 109 , 8391 (2013)

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However, this effect is largely eliminated by lowering Ero1 function through RNA interference, indicating that Ero1 activity in vivo leads to the production of ROS