"Obesity management medications work by suppressing appetite, increasing feelings of fullness, and altering eating behaviors, which often leads people to eat significantly less
Reflecting on the clinical implications, St-Pierre says that the findings support cautious use of GLP-1 RAs in selected patients with IBD when prescribed for approved metabolic indications, with appropriate counselling and monitoring. At the same time, she noted that the findings highlight substantial evidence gaps and believes future research should move beyond proxy outcomes and incorporate prospective, IBD-specific designs that integrate objective inflammatory measures with robust metabolic phenotyping. Moreover, there should be special considerations on the effects of GLP-1 RAs on body composition of patients with IBD, she adds
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Sattar N, Neeland IJ, Dahlqvist Leinhard O, Fernndez Land L, Bray R, Linge J, et al
The pre-treatment assessment should include a detailed medical history covering cardiovascular disease, diabetes, thyroid disorders, gallbladder disease, pancreatitis, and previous weight loss attempts
Some people also find that exploring complementary approaches to managing appetite and habits adds another layer of support alongside their prescribed treatment