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Like many essential compounds, its levels can decline due to age, stress, and environmental factors

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J Pharm Pharmacol 69(12):18581870 Maresca M, Micheli L, Mannelli LDC, Tenci B, Innocenti M, Khatib M, Mulinacci N, Ghelardini C (2016) Acute effect of Ca p pari s s pino s a root extracts on rat articular pain

(2008) 295:G26072