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Some of the beneficial effects of first-generation COX inhibitors may have been due to decreased levels of prostaglandin E 2 (PGE 2 ), which acts through GPCRs, some of which are expressed in cells along with the GLP-1R [18] and could modulate GLP-1R effects

[DOI] [PubMed] [Google Scholar] 52.Valderas JP, Ahuad J, Rubio L, Escalona M, Pollak F, Maiz A

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