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Interestingly, PPAR/ regulate the differentiation of adipocytes, keratinocytes, bone, and several immune cell types and promote the expression of genes related to lipid metabolism and mitochondrial biogenesis 67,68,69,70,71,72,73 , yet their function in SC- cell differentiation had not previously been observed

Liver biopsy should be considered in atypical clinical situations (e.g., patients with normal BMI or highly elevated liver enzyme levels)