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The causes of serotonin dysregulation in the brain are as follows: Genetic Predisposition : Some individuals have genetic variations affecting the serotonin transporter gene, leading to altered serotonin signaling and increasing their susceptibility to mental health conditions such as depression and anxiety

BPC 157 is a peptide that stands for body protection compound-157

doi:10.22074/ijfs.2021.6236

These include: Pernicious Anemia: An autoimmune disease that stops the stomach from making a protein needed for B12 absorption

So what do we know about BPC-157 and its potential as a PED

The Kraus 2014 Nature paper established that NNMT is highly expressed in adipose tissue (especially in obesity) and that NNMT knockdown in adipose protects against diet-induced obesity in mice