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[15] When there is high-frequency NMDA receptor activation, there is an increase in the expression of a protein PSD-95 that increases synaptic capacity for AMPA receptors

During this phase, protein tracking is mandatory

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Several open-label studies have reported a symptomatic benefit of salbutamol as add-on therapy to levodopa in PD [208,209,210], and it is currently being tested in an ongoing phase 2 parallel-group disease-modifying PD trial [211]

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