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Signs of mild to moderate dehydration include thirst, a dry or sticky mouth, not urinating much, darker yellow urine, dry skin, headache, and muscle cramps

354 GLP-1RAs and musculoskeletal health GLP-1RAs and bone The quality of bone depends on bone metabolism, and the main factors affecting bone metabolism include osteoclasts, osteoblasts, and calcitonin

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VSMF: vascular smooth muscle fiber

However, heterogeneity in weight loss response, cost, side effects, and need for injections may limit their use in many pediatric patients [23]