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Cholangiofibrosiscentral portions become atrophic, collagenized, and avascular whereas the active proliferating portion is at the periphery

It was administered for 14 days via oral gavage ( 4

In food-induced glucose-intolerant and prediabetic cynomolgus monkeys, oral administration of RGT-075 improved glucose tolerance and reduced food intake and fasting glucose levels

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In some embodiments, the otic formulation or composition comprises about 0.01% by weight of the poloxamer