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AOD-9604 does not cause water loss or glycogen depletion the way GLP-1 agonists do, so there is no early "whoosh" effect
Poor sleep may compound the muscle-loss risk on GLP-1 therapy Kion Sleep here Consider a blood panel To rule out iron deficiency, B12 depletion, or vitamin D insufficiency as contributing factors A Note on Rate of Weight Loss Very rapid weight loss on GLP-1 medications (more than 11.5 pounds per week on average) significantly increases the proportion of lean mass lost