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GLP-1 Receptor Agonists [review article]

2016 Apr;229(1):1-12

The SURPASS and SURMOUNT trials demonstrate the effectiveness of tirzepatide in improving glycaemic control and promoting weight loss in obese individuals with and without T2D, approaching levels seen from bariatric surgery

However, insulin remains essential for some patients, particularly those with severe hyperglycaemia or significant beta-cell failure

Faster weight loss means shorter treatment duration to reach a target, lower total compound consumption, and earlier access to the metabolic health benefits that accompany weight reduction

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