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Unlike Vitamin E, Vitamin C, or other antioxidants such as polyphenols, SOD is an enzyme and is not consumed in the process of neutralizing free radicals

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In fact, the two typically work together

A safety study on intranasal glutathione found it to be helpful for symptoms in 62% of patients with 12% reporting side effects

P., Dizikes, L

[33] Although the enzyme is functionally limited to the conversion of superoxide radicals into less toxic oxygen-containing molecules, methodological approaches utilizing phylogenetic and structural protein analysis suggest that three SOD isoforms have evolved independently to combat superoxide accumulation