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Description

c , Protein levels from cancer cell lines from DepMaps CCLE (Proteomics GGT1: P19440 (n = 339), GGT5: P36269 (n = 108), GGT6: Q6P531 (n = 45), GGT7: Q9UJ14 (n = 375))

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Subsequently, degradation of IRAK1 leads to the activation of IKK and IKK, which, in turn, triggers NF-B activation and downstream mediator production (79)

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