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Wang and his team developed new drugs based on furosemide to target both A accumulation and brain inflammation, which are key factors contributing to AD (112)

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Its core pathological feature is excessive accumulation of adipose tissue, accompanied by abnormal proliferation, differentiation, and metabolic dysfunction of adipocytes, which in turn induce a series of complications including insulin resistance, nonalcoholic fatty liver disease, and cardiovascular diseases

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TB-500 was initially studied for its ability to regenerate heart tissue after heart attacks

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Sept 21: In a setback for Intarcia Therapeutics, the FDAs Endocrinologic and Metabolic Drugs Advisory Committee voted unanimously that the benefits of its drug-device combination for Type 2 diabetes, ITCA 650, did not outweigh the risks

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