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Ponirakis, G

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Significant results are typically visible by 3 months, with continued progress over 1218 months of treatment

Acknowledgements This work was supported by the Department of Defense Breast Program under award number BC050277 Center of Excellence (VCJ)

Molecular structure and enzymatic activity of DPP-4: 2.1.1

Using C2C12 mouse myoblasts, the study confirmed that the MGF E-domain peptide increases myoblast proliferation while inhibiting terminal differentiation and critically, that this effect was maintained in the presence of a neutralising anti-IGF-1R antibody directly establishing that MGF E-peptide signals via an IGF-1R-independent mechanism