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High levels of GSH inhibit GSH synthesis by blocking glutamate cysteine ligase (GCL) (EC 6.3.2.2) [59]

intracellular half-life is prolonged because of lysosomal release and cytosolic resequestration, creating a depot effect that supports monthly maintenance dosing for chronic deficiencies

This type of supplement is commonly used to support the bodys antioxidant defenses, which help limit oxidative stress (cell damage caused by reactive molecules formed during normal metabolism, pollution exposure, UV light, illness, and aging)

This suggests that these proteins do not play a major role in the transport and breakdown of putative glutathione-AITC conjugates