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Using a diet-induced obesity model in mice, this study demonstrated that Lactobacillus rhamnosus PL60 can reduce body weight without affecting energy intake, specifically by decreasing the mass of white adipose tissue (epididymal and perirenal fat)

Its worth noting that the risk of side effects may vary from person to person, and some individuals may not experience any adverse reactions

The vaccine works through the immune system, which remains fully functional in GLP-1 users

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10.1016/j.ypmed.2011.12.028 118 WilliamsonR

Treatment with GLP-1RAs can reduce monocyte/macrophage accumulation in the arterial wall by inhibiting the adhesion of monocytes to activated endothelium from the arteries of C57BL/6 mice as well as in ApoE -/- mice [64]