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Stop taking Ozempic and seek urgent medical help Persistent vomiting preventing adequate fluid intake Signs of dehydration dark urine, dizziness, reduced urination Symptoms of hypoglycaemia shakiness, sweating, confusion, rapid heartbeat Visual changes or worsening of diabetic retinopathy Signs of allergic reaction rash, swelling, difficulty breathing (call 999 for severe reactions) Most side effects improve as your body adjusts to the medication

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Whether this pattern continues with future compounds remains to be seen, but retatrutide represents the current peak of incretin-based weight loss pharmacotherapy

Group III (10 patients) received oral placebo capsules (as a control) once daily for 4 weeks