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Evidence and Research Comparison# Semaglutide Research# Semaglutide has one of the most extensive clinical evidence bases of any peptide therapeutic: SUSTAIN trials : Seven Phase 3 studies in type 2 diabetes demonstrating HbA1c reduction and weight loss STEP trials : Four Phase 3 studies in obesity

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It should be noted that the trial population as a whole had a long duration of diabetes and suboptimal glycaemic management at baseline, both of which are well-known risk factors for diabetic retinopathy

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