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Alcohol depletes glutathione: Chronic alcohol consumption severely reduces hepatic glutathione through increased oxidative stress during ethanol metabolism [6][35]

10.1038/35097565 35 Courchesne-LoyerA.CroteauE.CastellanoC

M-Mode Echocardiography in Canine Veterinary Practice: A Comprehensive Review of Left Ventricular Measurements in 44 Different Dog Breeds

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Interestingly, both hypoxia-driven PE (PE2) and inflammation-driven PE (PE3) exhibited increased levels of oxidized nucleotides, when compared to parental-driven PE (PE1) and controls (Fig 1I and J)