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Mechanism of huanglian wendan decoction in improving impaired glucose tolerance based on skeletal muscle NLRP3/caspase-1/IL-1, IL-18 pathway

It was first isolated from human plasma in 1973 by researcher Loren Pickart, who discovered that older human serum caused liver cells to behave more like younger cells

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Further, we described that LDHB protects specifically KRAS-mutant lung cancer cells from ferroptosis, mainly of the plasma membrane, by maintaining SLC7A11-mediated glutathione metabolism 24