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Alcohol- and other substance-use disorders may well benefit from the effects of GLP-1RAs on dopamine and opioid pathways that are dysregulated in addiction 243 , as seen in some of the studies we identified, and the same could also apply to other under-investigated disorders with similar underlying dysfunctions (for example, gambling disorder)

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A 2011 study looked at the effects of alpha-lipoic acid supplementation over two months on fasting blood glucose (FBG), insulin resistance (IR), and glutathione peroxidase (GH-Px) activity in type 2 diabetics

Surgical considerations GLP-1 medications require careful management around any surgical procedure