In one of the landmark studies that supported the use of this drug for weight loss, the individuals who were on the drug actually lost a meaningful amount of lean mass, not just fat mass
One day your skin is glowing, and the next it suddenly looks dull, tired, oily, uneven, and impossible to fix no matter how much skincare you use
Increased ability to burn fat and build lean muscle
The FTC's December 2025 enforcement action against NextMed was specifically about failure to disclose that an advertised telehealth price didn't include medication costs
From a biochemical standpoint, pushing the balance too far toward NADH relative to NAD plus can disrupt redox balance, which helps explain why overly aggressive dosing or stacking multiple NAD approaches may increase side effects rather than benefits
2004;171:S1924