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Simultaneously, catalytically produced hydrogen peroxide (H 2 O 2 ) activates the protein transient receptor potential melastatin 2 (TRPM2) ion channel, promotes calcium influx, activates macrophages, and induces systemic immune response (Fig

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Gradually both AST and ALT declined on day 07 of admission while ALT had a significant reduction (p = 0.013) compared to the day 05 of admission