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Activation of the peripheral nervous system likely occurs primarily through stimulation of the hepatic vagal nerve in the portal area

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Regular aerobic exercise improves cerebral blood flow, promotes neuroplasticity, reduces inflammation, and enhances mood

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Obesity is associated with 13 types of cancer, increased surgical complication rates, lost work productivity ($1,784 per obese worker annually), and reduced life expectancy of 5 to 14 years depending on severity