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BPC-157 has a half-life of approximately five days, meaning it takes four to five weeks for the medication to be more than 99% cleared from the body

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[DOI] [PubMed] [Google Scholar] 45.Urata Y., Yamamoto H., Goto S., Tsushima H., Akazawa S., Yamashita S., Nagataki S., Kondo T

No serious adverse events have been reported at therapeutic doses

Hypoxia/reoxygenation (H/R)-induced cardiomyocyte injury model showed significant downregulation of miR-494-3p mRNA expression, upregulation of PGC-1, PINK1, and Parkin protein expression, downregulation of Mfn1, Mfn2, and OPA1 protein expression, and reduction of mitochondrial MMP, suggesting that H/R induced excessive mitophagy in cardiomyocytes

Nucleic Acids Res 43(D1):D222D226