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But some users do report mild side effects, including: Headaches or dizziness (typically at higher doses or when stacking with GH-related peptides) Injection site irritation , redness, or swelling Nausea or GI discomfort when taken orally (more common with low-quality forms) Changes in mood or energy , including restlessness or mild anxiety These symptoms are usually temporary and resolve quickly with dosage adjustment or cycling off

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Tryptophan catabolites from microbiota engage aryl hydrocarbon receptor and balance mucosal reactivity via interleukin-22