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Harvard Health Publishing, Harvard Medical School

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Lilly and Nimbus have been partnering for more than three years on developing a small molecule activator of a specific isoform of AMP-activated protein kinase (AMPK) to treat cardiometabolic diseases, under an up-to-$496 million partnership launched in 2022

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In this longitudinal study, magnetic resonance spectroscopy (MRS) was used to measure metabolite levels in the thalamus, sensorimotor cortex and visual cortex over two sessions (on average 3 years apart) in participants ages 7-18y

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