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In a study on adipocytes from healthy women, it was observed that testosterone, acting through its receptor, induces IR in these cells by affecting insulin-stimulated phosphorylation of protein kinase C (PKC) (Figure 2) [38]

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G-I) Songbird differential ranking of microbes (G), fecal metabolites (H) and plasma metabolites (I) (association with response compared to no response as the reference)