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Roth J, Glick SM, Yalow RS, Berson SA

Neuronal survival and neurogenesis Neuronal survival is reduced in AD due to the induction of neuronal apoptosis, necrosis, ferroptosis, and pyroptosis by A and tau protein, and associated neuroinflammation, oxidative stress, ER stress, and mitochondrial dysfunction (Mangalmurti and Lukens 2022

If there are concerns about a false positive result due to pantoprazole use, work with the prescriber and pharmacist to understand the next steps

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This is an exciting example of how therapies developed for one disease may ultimately reshape the management of another