In animal studies, GLP-1 receptor agonists have been associated with thyroid C-cell tumours, though this finding has not been established in humans
Retatrutide tends to target the three key hormone receptors, including glucagon-like peptide-1 (GLP-1), glucose-dependent insulinotropic polypeptide (GIP), and glucagon receptors in experimental models
The Risks, Side Effects, and Why Careful Dosing of GLP-1 Matters GLP-1 medications like Ozempic, Wegovy, Zepbound, and Mounjaro have helped many people lose weight, Disclaimer: This blog post is for informational purposes only and should not be considered medical advice
Review By HARMINDER HARMY KAUR Last Updated On : Mar 13 2026 BSc(hons) Pharmacy GPhC Number: 2061107 Authored By GURDEV SEHMI Last Reviewed On : Mar 23 2026 BSc Pharm, MRPharmS, Independent Prescriber, Superintendent Pharmacist, Clinical Lead GPhC Number: 2050925
However, in the late 20th century, scientists discovered the "Incretin Effect." They noticed that oral glucose triggered a much higher insulin response than intravenous glucose
With these drugs, the main side effects are nausea, vomiting, constipation, diarrhea, and other gastrointestinal issues
