MR-Egger regression indicated no significant horizontal pleiotropy (Supplementary Table S6), supporting the validity of our primary findings

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While the genetic background of the individual with idiopathic vitiligo strongly influences the disease development preventing a successful recovery, the occupational vitiligo is generally induced by exposure and the return to the skin repigmentation is feasible, once the agent to which the subject is exposed to is removed from the work environment
No reliable clinical evidence for 5-Amino-1MQ was identified