73 The treatment increased -catenin expression and suppressed RANKL activation, suggesting that semaglutide may promote osteoblastogenesis and inhibit osteoclast-mediated bone resorption through the Wnt signaling pathway
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The consensus, if one exists, is this: split dosing is a pharmacologically reasonable modification that has not been clinically validated
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* Correspondence: Pablo Albertos, [email protected] Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers