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Mechanistically, the treatment improved insulin sensitivity and glucose uptake, particularly in brown adipose tissue, with glucose uptake similar to that of GLP-1GIP in several other metabolic tissues, without increasing energy expenditure or promoting adipocyte differentiation

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One of the most common and devastating severe manifestations of SLE is lupus nephritis (LN), which affects an estimated 40-70% of lupus patients

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And thats a pretty easy rule of thumb