As a general rule, IM is favored when the goal is rapid correction of a clinical deficiency, when the patient has difficulty absorbing B12 through oral or sublingual routes, or when a provider wants predictable peak serum levels
Unlike oral supplements, these injections bypass the digestive system and deliver B12 directly into your bloodstream, making them ideal for people with absorption issues or chronic deficiency
Simultaneous administration of potassium-sparing diuretics may be associated with increased serum potassium concentration
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Vitamin B12 is a water-soluble nutrient, which means your body absorbs what it can use and naturally gets rid of the rest