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For weight management, NICE recommends semaglutide 2.4mg (Wegovy) for adults with a BMI 35 kg/m (or 30 kg/m with weight-related comorbidities) within specialist weight management services alongside lifestyle interventions (TA875)
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However, this composite score did not change significantly in the L-Carnitine group ( P = 0.232), and decreased slightly in the placebo group ( P = 0.534)
Liraglutide has a longer overall safety track record, having been approved for weight management since 2015, compared with Wegovy, which was approved in 2022
ACS Synth Biol
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