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The tradeoff
A patient losing 30 pounds with semaglutide over 12 months would pay approximately $200-250 per pound lost with compounded versions, while a Contrave patient losing 15 pounds would pay approximately $200-300 per pound lost
Per a study published in April in Genome Medicine , people who carried certain mutations in their PAM (peptidyl-gylcine alpha-amidating monooxygenase) genes, which are key for processing hormones, were less likely to respond to GLP-1 drugs
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Louis Aronne is a paid consultant and advisory board member for Eli Lilly and Company, the study sponsor and the manufacturer of orforglipron and tirzepatide.
Novo Nordisk terminates collaboration with Hims & Hers Health, Inc
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