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Although the loss of pigmented dopaminergic neurons in the substantia nigra and the deposition of -synuclein in neurons are not exclusive to Parkinson's disease, their combination is necessary for a confirmed diagnosis of idiopathic Parkinson's disease [17]

Ashour AE, Sayed-Ahmed MM, Abd-Allah AR, Korashy HM, Maayah ZH, Alkhalidi H, et al