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There is one significant genetic polymorphism of the ALDH2 gene, resulting in allelic variants ALDH2*1 and ALDH2*2, which is virtually inactive

It also affects metabolic pathways, nutrient uptake, and cellular regeneration in experimental models

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Overall, nutraceuticals and targeted vitamin/mineral supplementation are viewed as strategies that can provide modest benefits with minimal adverse effects in managing various ASD symptoms

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In an untargeted analysis, we identified a high degree of homogeneity across all sample groups at the global scale (Fig