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Its ability to penetrate the BBB, its metabolic stability, and its significant efficacy in restoring cognitive and motor functions in animal models of AD and PD, likely through modulating the HGF/c-Met system, position it as a highly promising therapeutic candidate for these debilitating neurodegenerative diseases [2]

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Inhaled glutathione preparations may trigger respiratory symptoms in individuals with asthma, including wheezing or breathing difficulties

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Further, its anti-asthma effects were also improved, evidence by improved asthma-associated inflammation, including eosinophil production, OVA-specific IgE, IL-4, IL-5, and IFN- at 10 mg/kg compared to the group that received 20 mg/kg of free isoliquiritigenin [116]

IL2-inducible T-cell kinase inhibitor ibrutinib reduces symptoms and Th2 differentiation in mouse allergic-rhinitis model