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Tirzepatide (sold as Zepbound for weight loss, Mounjaro for diabetes) produces the most weight loss of any approved drug: about 22.5%

Thirdly, GLP-1 agonists slow gastric emptying, leading to a delayed absorption of nutrients and a prolonged feeling of fullness, which can contribute to reduced food intake and weight loss

At 4mg, that number nearly doubled to 17.1%

264,268 Released at the guts end, GLP-1 acts on its receptors in the gastrointestinal tract, leading to reduced gastric muscle contractions and extended food retention in the stomach

Acknowledgements We thank the 23andMe research participants and employees who made this study possible

They found that people taking GLP-1 medications had a 40 percent lower risk of pulmonary embolism (PE), the potentially fatal condition that occurs when a blood clot travels to the lungs