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Increasing fiber and water intake during weeks 1 to 4 helps prevent this from escalating when doses go up

24 The nature of the relationship between obesity and PCOS appears to be bi-directional, with each contributing to the onset and progression of the other

Most patients experience these symptoms as mild to moderate in severity, with a relatively small percentage discontinuing treatment due to gastrointestinal effects

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(4) patients not diagnosed with MASLD