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Hepatocytes represent the majority of liver mass, while non-parenchymal cells include KCs, hepatic stellate cells (HSCs), liver sinusoidal endothelial cells, and infiltrating immune cells such as lymphocytes and neutrophils

This fact further raises the possibility of practical applications targeting IGF-1R

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Enhanced Fat Metabolism: Once inside the mitochondria, these fatty acids can be burned (oxidized) to produce energy, thus promoting efficient fat metabolism

Sulforaphane inhibits cGAS activity by dose-dependently blocking the binding of dsDNA-cGAS [416]