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More recently, the combination of GLP-1 Ras with GCG RA or with GIP RA in NASH murine models allowed one to achieve additional weight loss and, more importantly, to determine a greater improvement in histological NAFLD activity score compared to treatment with mono-agonists [172]

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(3) Activation of GLP-1R suppressed microglial morphological changes and inflammatory factor release in the TNC in CM mice and in vitro

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