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doi: 10.3390/ijms10125326

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Clinical trial data shows that gastrointestinal side effects occur in 1530% of tirzepatide users, with severity ranging from mild discomfort to nausea that requires dietary modification

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Thus, GABA from reactive astrocytes diminishes the spike probability of the perforant-path-to-dentate-granule-cell synapse, leading to impairment in synaptic plasticity and memory function

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