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Using alcohol-free mouthwash may also be beneficial

Placebo capsules comprised microcrystalline cellulose (REDWELLS HEALTH LTD, London, UK) combined with 10% (w/w) gum Arabic (CAS 9000-01-5, Willy Benecke, Hamburg, Germany), matching the gum Arabic content of the pomegranate extract, and 1% (w/w) brown food coloring (rainbow dust edible powder color, Cake Decorating Co., UK) to ensure that the pomegranate and placebo capsules were identical in appearance

Moreover, NADPH oxidase content was measured using a specific ELISA kit obtained from ELK Biotechnology (Wuhan, China

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