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A marked reduction was observed in protective phyla, including Bacteroidota, which was significantly decreasedcompromising SCFA production and gut homeostasisalong with a substantial depletion of Actinomycetota, a phylum containing Bifidobacterium, indicating impaired immunomodulatory capacity

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This is now well documented with two different methods: immunohistochemistry (in the present study) or autoradiography

The controversy surrounding MTHFR stems from conflicting medical opinions

Although fatigue prevalence fluctuates concerning cirrhosis etiology, ranging from 44% in autoimmune liver disease to as high as 80% in primary biliary cholangitis (7), it is noteworthy that this symptom may not necessarily correlate with the severity of underlying liver fibrosis, advanced disease stages, or organ dysfunction

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